Development of stable, repeatable formulations for lyophilised vials, fixed-ratio blends, liquids and intranasal formats.
A compound is only useful in research if it can be prepared the same way every time and stays stable until it is used.
Formats
Formulation work starts with how the material will be used in the laboratory. Lyophilised vials suit sensitive materials that need protecting in storage. Fixed-ratio blends combine compounds in a defined proportion. Liquids and intranasal formats have their own requirements for concentration and stability.
Development
Excipients and buffers affect how a material dissolves, how it holds up over time and how it behaves in its final format. Choices depend on the properties of the material, the concentration required and the storage conditions.
Candidate formulations are prepared and assessed against the agreed specification.
Transfer
Once a candidate meets the specification, the formulation record and production instructions are written up so the work can be repeated.
Stability data supports decisions on storage and handling, and the documented formulation can be transferred to pilot or batch production.
Scope, equipment and accreditations for this service are to be confirmed before publication.
The process
Four stages take a formulation from specification to production instructions.
Format, concentration and storage requirements are agreed.
Candidate formulations are prepared.
Candidates are tested against the specification.
The selected formulation is documented for production.
Scope
Outputs
Facilities and infrastructure
One company, five locations across the UK, the Netherlands and India. Every service is backed by the same lot records, wherever the work happens.
United KingdomBridgendFormulation, production and manufacturing
ISO 7 accredited
GMP certified
United KingdomWickfordHPLC, analytical testing and freeze-dryingISO 7 accreditedGMP certified
United KingdomThetfordUK warehousing, cold-chain storage and distributionLot-tracked stockCold-chain storage
NetherlandsAmsterdamEU warehousing, cold-chain storage and distributionEU distributionCold-chain storage
IndiaBaddiBiologics facilityBiologicsGood to know
Send your current details and specification, and we can review them with you.
Tell us how the material will be stored and shipped, as this affects the approach.
If the format is a lyophilised vial, formulation and cycle development work closely together.
Questions
Lyophilised vials, fixed-ratio blends, liquids and intranasal formats.
Yes. Send the current formulation details and specification with your enquiry.
Start a project
Send your requirements and we will confirm the scope, documentation and lead time. It helps to include:
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